For emergency treatment, EpiPen delivers 0.3 mg I.M. or follow with a continuous infusion of 1 mcg/minute, increased to 4 mcg/minute p.r.n. slowly over 5 to 10 minutes may repeat q 5 to 15 minutes p.r.n. ➣ Bronchodilation anaphylaxis hypersensitivity reactionĪdults: 0.1 to 0.5 ml of 1:1,000 solution subcutaneously or I.M., repeated q 10 to 15 minutes p.r.n. It is also used topically in the eye in the treatment of glaucoma. It is the most effective drug for counteracting the lethal effects of anaphylactic shock. It acts as a vasoconstrictor, antispasmodic, and sympathomimetic, and it is used as an emergency heart stimulant as well as to relieve symptoms in allergic conditions such as urticaria (hives), asthma, and other conditions requiring bronchodilation and as a adjunct to local and regional anesthesia. Removal of the tumor relieves symptoms.Įpinephrine is also produced synthetically and can be administered parenterally, topically, or by inhalation. Certain adrenal tumors also result in the production of too much epinephrine. By contrast, excessive activity of those glands, as sometimes seen in highly emotional persons, tends to produce tenseness, palpitation, high blood pressure, perhaps diarrhea, and overaggressiveness. Some disorders of the adrenal glands, such as addison's disease, reduce the output of epinephrine below normal. It also increases glycogenolysis and the release of glucose from the liver, so that a person has a suddenly increased feeling of muscular strength and aggressiveness.

Epinephrine is a powerful vasopressor that increases blood pressure and increases the heart rate and cardiac output. At times when a person is highly stimulated, as by fear, anger, or some challenging situation, extra amounts of epinephrine are released into the bloodstream, preparing the body for energetic action. Its function is to aid in the regulation of the sympathetic branch of the autonomic nervous system. A hormone produced by the adrenal medulla called also adrenaline (British).

Too much epinephrine disorders